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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86122ebca402b5242bef2589b79a5c2f86d3e809306b8aed3b8850be044c89c2' 
  AND token = 'HTIDNA7U6ETD/mK11xhb9fr5LI2Jv0xcWNuMdIOzIHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}