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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6041f6a3d72ff74c90ab4a74fe4807f0f1b51fde35d330b445459efa9910962' 
  AND token = '3HmsYPJRCFXnYK8p85AmY287wgblVcQ1UxPYp6uwGe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}