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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492547fee9a843681a063364569233e60632b6f6c9d2ffd3dc668beda9678ab0' 
  AND token = '2xJVXe4Ke5T384kb+QzqWEcbQSjNHNDLbTVYA1YnfcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}