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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1beb0158635df66547864255e93ce1e77bc8e2778da9f1a81afc19cb284f5e7c' 
  AND token = 'OHV9Fa1mx91+qQandmR9FDPeIt/6a/erV50a/fuT3Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}