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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03fa9d069c827bc9563a4814056a97f8981dea3fb7008883c15fcb800d2403de' 
  AND token = 'VNEjxAR8hirv3aBCl8dq77wwRBWeWHQZrafa5xyr/R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}