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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7632cbe0429b8e4020ed784f38cdf1f33d46015f2f3448e28a9f41e115d7cc' 
  AND token = 'ir0v42rLEvk6VJg/oMt7vkD5qNl+056VI+s06OTuQpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}