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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4af0a673222cb649a08bd676df2da8c55f1fccca97a14c453bbd48c15250a85' 
  AND token = 'NJFTp7s4CG9/ckgkjIqUlSE5Sc4hN7IhEvHZn5KGg30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}