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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d11026c3442a65edbae5a83c78143f86e265c9852d817163df9e0a592bf2b44' 
  AND token = 'Vky+MQzo0n2DZBzvxOWTRg8M9XO+e8HomISkg0Eh2UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}