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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6283e0ac4f183ba8df1f83bb48f64288301e6465d6f9d4f0c9812f74522e54d5' 
  AND token = 'cyHyQFqI8wCz9GE8C4LnBzUWWgDXeDgDSOtKvoUnPHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}