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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e04d56d40abb49d1e3edccbea837c5ee9c7e657c32dbf7ff6582fb40506187d' 
  AND token = 'D0T2aR9aLjlxNTiHzAWr2d+HvZnAhonV2iH6Zg2lfTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}