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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10da063222fc49e0a38ac7aa168553d5ee1da212d5dc31c834f118d37904b9d' 
  AND token = 'LxIxGUCcSgD/xTWu8K0/beSLur3xuLOmuGBRUqi2DeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}