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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f6ef7fe08b51fcd4ae9784f7fab4d84efa025b4071b9718e7ae395c711f11d7' 
  AND token = 'KmUGeTDAslNZOVR+mCMkqHHaQ680VRHQjLn6bLae8Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}