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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be5f63fda9dba52ec6c5202dc8b9195a67abea82b6d01e582a91f66aa9c3ee6' 
  AND token = 'kZRzHJ+nd37YNth7kRyoBYt3jB+wJ7906rqcuEm7IaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}