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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356cd0cf0eba74ac51e548325f905da038d07522236c1ae5e17905873d41cc62' 
  AND token = 'Yzy/aVk9LpwQ+E92+HdQ3RmtpeclX33rB3ut1hMoVCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}