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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111e3e5697263c4bc5dcc80f1ac1e07f46f50fcd647ff053255dd44aecdbbfec' 
  AND token = 'ZBExoFT07NGfoU1B0gi1/XhMY2odpds4Jfy99uAUAUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}