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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde8673a035985f9b89e42ca5df191074ce0aac5f8bb1eb479d7201f080be736' 
  AND token = 'ZgmmTHj/QcHnes0YZ1gKVUnzs8kO1SAmi2X3Ve2nJ8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}