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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6237b08d5469257de2fda4e50fdcab132bdb97351aaa4ddb76c24a1098fe3a85' 
  AND token = 'prr7CoD0tMnFC65VX7MMA3O/1A7R8h+8ZyqZ10fDg+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}