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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1095f51a0671363e7722877fc4e90862efe4445e66142ac1f988f915c7e69b78' 
  AND token = 'g+BzS6XO9IdH9vFKsQ2HvOYvzPAJN1ageo8Oui79pks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}