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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18925c155ea2087f679c7f0ec4a862fce553cd153a12a8e978758400adecde78' 
  AND token = 'Xd/xRIjNaq1d0XAfL/NwjLY9reEaYCAIYbXMgIxRTDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}