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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dcaba56598e51700ad25d2c2358cf18894f36050e07b85a5299f3a769b87f97' 
  AND token = 'LLNFPE4s8zSUWy3AQeuAC+DX4ABlWd1XAy86f/TtkZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}