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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1cb2a81d062270956e2e219cd1e1b88427aaa3f18759cc6f26c000c86ab0b42' 
  AND token = 'wa7Um35pSe8SfQ0CBezy72k5lK60aqT8Xiw5uy5FdIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}