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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9be64d6c503dbf1242d9121565051c74cfe55362aa8aa1f5f3029f5250dc7a3' 
  AND token = 'ruJTqxsunbZJOIwjjPARUlmXTG6hX1sy5TJ5a1kLYMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}