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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a318463422d802936c3603767980716352ade0f61827d57dd798d5c7315208f' 
  AND token = 'FamqLeyCZ0dZ3wHTI6zqSU1HGWE02kVWLnZ3JiiQQ30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}