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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161b7754d106e00b8bd278c6d2cc5d372581322f2cd19694ac886d0c1936eadf' 
  AND token = 'bc2LR1eJg4jCDRkPYjDtaE4zRJ3klUAWZ4QPDqMAtxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}