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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd24369361d113cc155bad4449fe058e967208baaf6e4303ee27ea2798b4a7c67' 
  AND token = 'cG51HYNipufp20tfeVSfyk51VYVLOd/GvOjRwMSv07c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}