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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e245fa00f297e45cae0eb779c1a55dbeef338f1c389d317948dcd9954c54f8b7' 
  AND token = 'rEm66tW428g2k+Q1WL5SLB5lVLcosN8HPPYcYRICWsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}