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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b77825c1d3751508018e0ad222c4af78c29a9631e09979eaeee9782c597c208' 
  AND token = 'ZCYO0TYmYSq1MStEYLOO1t4c7CqZKVl/6lBW5YZ8lCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}