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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c295f23744cb4510f605251faa3c23c4557a35f86eb2a35cdf6faeb2ba803062' 
  AND token = 'aAQSD8vWtr3ckPTl+GdahIEkVv6pIBMN9gLx0bjuWzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}