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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a525949fd8aa9c67138e2a9372d249d054cceec1326e31666cb524a3524a788f' 
  AND token = 'sg7x2sMMgIpW/utzw6EBUbbsgFKBkA2a1LWh+xQdwc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}