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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce646edbf8f93c49ca6e58455db83e40416336317e4504ce241db1a2a78555e' 
  AND token = 'hzlEwu3r5/9x/Cf2AVndn2ZrW9Egzt81ZdwmU0rEeqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}