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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469a3f64a507b27cc9c7216a59ff45620e8f19197ae48db73d6822c08640ed6c' 
  AND token = '5T4NzQR6ZFZfgPlUMCzMgAw7GEatheK0aNGwiTIMxe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}