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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e68f23e5fc60d20beb90707f5b30585722475b20a286b60753235d5a6d394bc' 
  AND token = '2wwvUw33cbzsCl5dlz2rniYfmmCsXAWkFdtY2CUK9/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}