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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8f4c54810e341e42a86e59d1972c822110c830480c2c391c3cf909907fbdeb' 
  AND token = '/fvItaclk9TR5sBk9dB+GDrhnd/wsVshaZn9n+5lzNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}