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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee5fcb5cf0e3ed9971327c13d2071e7db3b01bcd5c290f465523b31f711e5c4' 
  AND token = '3KHkWH2rlj3ffg4BcYiFT5UQT7C8n65WQqGtzPbm1ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}