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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b5645e0a0588aae103162295e6e78ee7c8bdbf695469b4004ca02b04188bab' 
  AND token = 'Vb+47gF3qLThQ3gxWB8r2O/GxQ9uzIdRd75ExFST+Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}