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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721813663af1f4177f4462f15eda277b9fd51756cccffa5a0931b446472323e0' 
  AND token = '7dUnFCC6Amrwhx2D+j7yfLjZc+NAMKbfMueKxARN22g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}