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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a6882ab09e840659fe8ed951ad3f245912057b033b3653deda00b9255ad2cf' 
  AND token = 'aCTLW/2jsbIw/uZ8PFJ0iCp3wn1IW+5Nt5+TM1e+yOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}