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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09481180ad87e22e1deaca5fc7115a532cfe4a479ff4580b4f78816a2103e815' 
  AND token = 'inPpfO/25S15oF59W4CaSifYLsnUDj6gPBymRqPHPx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}