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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ef1fe8a1768af4359cbb807fb1cd40c901ce9bebc8161412dc1c46e0dfbb05' 
  AND token = 'mvo+9jnL5JHr5LnNZgbpCDWzpSQea37aUKO9zCPifMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}