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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffdf91d4cf25dfdecefa05489621eb9561ab1b757cec98a6cda7cafcf77642f' 
  AND token = '4NdF3oh7/w8F+qfGABB4B1RPyAMk1rs/meWK6PY0ik8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}