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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd0f23b70fd00d47202454716f34138023d391ba0cff7dfa8c2729ffc2181fe' 
  AND token = '4rsXs0x6sO0w4DtMmLXosG7+liGpuPl90rtJ67l+yZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}