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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108e144d790e5cbcd169768b395ae2e26b1deab09ff50d7879bac6a13b02e6bd' 
  AND token = 'igswdM7/czM4TtfzKP4gk3LNceBaTeP1Vv+zsDRoYHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}