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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb65d7a2ab37bcd760712fa64f82dcb7ad6153ad8acb6b335cb928d1da83e37' 
  AND token = '4msX4zjDlQRwVjxMpUe4ZkpN2+3Zt0x8T0lNOWj3apo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}