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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f193a1a4fbe4bde1d7440910b0cf783874a7bf44bc8a86619abd11890463cf6' 
  AND token = 'eoYHMOCFkPErt2cJqRQV2HclRhVKPe7EZ5+dXpKaXoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}