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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24586c858794e1aaf717fc3d1c7da3fa396cca4d6d920bba11756787b6e807b' 
  AND token = '+NXkDZze6UvB3Xw8x1CfF3ta0ogWJSxS1dBfhFW/M8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}