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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd132cd99450e54e2794713da0b2710e68b39f9148bd4f05c3e3aea8ff5613883' 
  AND token = '23zsRminPQyl6r3hghBFZy0ScfNE3rqHJz8NOAxqdKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}