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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f1e14d142e5b853d65b9cb3146d1f61a0552fe9398f4f7086d8c3f466a290c' 
  AND token = 'HujCZMi2bXXakR2lPbEMfv7kDQCbxT6xrNilLgG05Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}