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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a3b0f343368eb442ed80873f6b613e1a7675f2b88b7776acbc3d40b3f5f536' 
  AND token = 'sRhmMN3x7it9YnD+Hc/EFS9gSgF1SLAzlCfLg+Jn45U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}