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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1746f5606533e4539a1f850b78a9631c7a1a5ba796b0e5c0fa66f5fec4a63c9' 
  AND token = 'jBWoTl7MoyRTR4k4mxjLSnewoRIL4SZyH4vL7LTPHNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}