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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4accb95eeb0f831e95b97b756e03bd82493fc486678eb5b33861e207c0de578' 
  AND token = 'qYHy8hBdnvFKztG7k0amtM9zUCexgDLyyhTtp5wuPDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}